BSHI guideline: HLA matching and donor selection for haematopoietic progenitor cell transplantation
نویسندگان
چکیده
A review of the British Society for Histocompatibility and Immunogenetics (BSHI) Guideline ‘HLA matching donor selection haematopoietic progenitor cell transplantation’ published in 2016 was undertaken by a BSHI appointed writing committee. Literature searches were performed data extracted presented as recommendations according to GRADE nomenclature.
منابع مشابه
Sarcoidosis in donor-derived tissues after haematopoietic stem cell transplantation.
A 64-year-old Japanese female was diagnosed to have adult Tcell leukaemia in December 2009. She had neither any past history nor a family history of sarcoidosis. She underwent HSCT (unrelated bone marrow transplantation) in May 2010, after receiving treatment with fludarabine, busulfan, and total body irradiation, from a human leukocyte antigen (HLA)matched male donor who had no history of sarc...
متن کاملTRANSPLANTATION HLA-DPB1 matching status has significant implications for recipients of unrelated donor stem cell transplants
Studies in unrelated donor (UD) hematopoietic stem cell transplantations (HSCT) show an effect of the matching status of HLA-DPB1 on complications. We analyzed 423 UD-HSCT pairs. Most protocols included T-cell depletion (TCD). All pairs had high-resolution tissue typing performed for 6 HLA loci. Two hundred eightytwo pairs were matched at 10 of 10 alleles (29% were DPB1 matched). In 141 HLAmism...
متن کاملThe impact of HLA matching on unrelated donor hematopoietic stem cell transplantation in Korean children
BACKGROUND The impact of HLA matching on outcomes of unrelated donor (URD) hematopoietic stem cell transplantation (HSCT) varies in different racial or ethnic groups. Since little is known about the impact of such matching on URD HSCT in Korean children, we analyzed this issue. METHODS We analyzed the outcomes of 142 patients who underwent URD HSCT at 4 Korean medical centers. All patient don...
متن کاملImpact of HLA diversity on donor selection in organ and stem cell transplantation.
The human major histocompatibility complex is a multigene system encoding polymorphic human leucocyte antigens (HLA) that present peptides derived from pathogens to the immune system. The high diversity of HLA alleles and haplotypes in the worldwide populations represents a major barrier to organ and allogeneic hematopoietic stem cell transplantation, because HLA incompatibilities are efficient...
متن کاملDecision analysis for donor selection in stem cell transplantation—HLA-8/8 allele-matched unrelated donor vs HLA-1 AG mismatched related donor
Risk of relapse during the unrelated donor coordination period biases comparisons between allogeneic hematopoietic stem cell transplantation from an HLA 8 of 8 allele-matched unrelated donor (8/8 MUD) and that from a related donor with an HLA-1 antigen mismatch in the graft-versus-host (GVH) direction (RD/1AGMM-GVH). To reduce this bias, we performed a decision analysis focusing on acute myeloi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Immunogenetics
سال: 2021
ISSN: ['1744-3121', '1744-313X']
DOI: https://doi.org/10.1111/iji.12527